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SIRT1 promotes metastasis of human osteosarcoma cells

Pulmonary metastasis is the leading cause of mortality in patients with osteosarcoma; however, the underlying mechanism remains unclear. The NAD(+)-dependent deacetylase, sirtuin 1 (SIRT1), has been reported to play a key role in carcinogenesis through deacetylation of important regulatory proteins....

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Detalles Bibliográficos
Autores principales:	Zhang, Ning, Xie, Tao, Xian, Miao, Wang, Yi-Jie, Li, Heng-Yuan, Ying, Mei-Dan, Ye, Zhao-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346743/ https://www.ncbi.nlm.nih.gov/pubmed/27793039 http://dx.doi.org/10.18632/oncotarget.12916

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