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RSK2 activity mediates glioblastoma invasiveness and is a potential target for new therapeutics

In glioblastoma (GBM), infiltration of primary tumor cells into the normal tissue and dispersal throughout the brain is a central challenge to successful treatment that remains unmet. Indeed, patients respond poorly to the current therapies of tumor resection followed by chemotherapy with radiothera...

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Detalles Bibliográficos
Autores principales: Sulzmaier, Florian J., Young-Robbins, Shirley, Jiang, Pengfei, Geerts, Dirk, Prechtl, Amanda M., Matter, Michelle L., Kesari, Santosh, Ramos, Joe W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346757/
https://www.ncbi.nlm.nih.gov/pubmed/27829215
http://dx.doi.org/10.18632/oncotarget.13084