Adjuvant radiation therapy in stage I seminoma: 20 years of oncologic results

AIM: To report long term oncologic outcomes after adjuvant radiotherapy (RT) for stage I seminoma. METHOD: We reviewed the complete data set for all patients treated at our institute between 1988 and 2005 for stage I seminoma with adjuvant RT after radical orchiectomy. RESULTS: A total of 85 patient...

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Detalles Bibliográficos
Autores principales: De Felice, Francesca, Musio, Daniela, Gravina, Giovanni Luca, Marampon, Francesco, Tombolini, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Clinical Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346772/
https://www.ncbi.nlm.nih.gov/pubmed/27556300
http://dx.doi.org/10.18632/oncotarget.11374
Descripción
Sumario:AIM: To report long term oncologic outcomes after adjuvant radiotherapy (RT) for stage I seminoma. METHOD: We reviewed the complete data set for all patients treated at our institute between 1988 and 2005 for stage I seminoma with adjuvant RT after radical orchiectomy. RESULTS: A total of 85 patients were included. The median follow-up was 15 years. The 20-year overall survival (OS) and relapse free survival (RFS) were 92% and 96.3%, respectively. No severe acute and late complications were recorded. Overall 5.9% of patients had a second unrelated malignancy. CONCLUSION: Adjuvant RT is an efficacious and safe treatment in stage I seminoma.

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