Adjuvant radiation therapy in stage I seminoma: 20 years of oncologic results

AIM: To report long term oncologic outcomes after adjuvant radiotherapy (RT) for stage I seminoma. METHOD: We reviewed the complete data set for all patients treated at our institute between 1988 and 2005 for stage I seminoma with adjuvant RT after radical orchiectomy. RESULTS: A total of 85 patient...

Descripción completa

Detalles Bibliográficos
Autores principales: De Felice, Francesca, Musio, Daniela, Gravina, Giovanni Luca, Marampon, Francesco, Tombolini, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Clinical Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346772/
https://www.ncbi.nlm.nih.gov/pubmed/27556300
http://dx.doi.org/10.18632/oncotarget.11374
_version_ 1782513948602400768
author De Felice, Francesca
Musio, Daniela
Gravina, Giovanni Luca
Marampon, Francesco
Tombolini, Vincenzo
author_facet De Felice, Francesca
Musio, Daniela
Gravina, Giovanni Luca
Marampon, Francesco
Tombolini, Vincenzo
author_sort De Felice, Francesca
collection PubMed
description AIM: To report long term oncologic outcomes after adjuvant radiotherapy (RT) for stage I seminoma. METHOD: We reviewed the complete data set for all patients treated at our institute between 1988 and 2005 for stage I seminoma with adjuvant RT after radical orchiectomy. RESULTS: A total of 85 patients were included. The median follow-up was 15 years. The 20-year overall survival (OS) and relapse free survival (RFS) were 92% and 96.3%, respectively. No severe acute and late complications were recorded. Overall 5.9% of patients had a second unrelated malignancy. CONCLUSION: Adjuvant RT is an efficacious and safe treatment in stage I seminoma.
format Online
Article
Text
id pubmed-5346772
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Impact Journals LLC
record_format MEDLINE/PubMed
spelling pubmed-53467722017-03-30 Adjuvant radiation therapy in stage I seminoma: 20 years of oncologic results De Felice, Francesca Musio, Daniela Gravina, Giovanni Luca Marampon, Francesco Tombolini, Vincenzo Oncotarget Clinical Research Paper AIM: To report long term oncologic outcomes after adjuvant radiotherapy (RT) for stage I seminoma. METHOD: We reviewed the complete data set for all patients treated at our institute between 1988 and 2005 for stage I seminoma with adjuvant RT after radical orchiectomy. RESULTS: A total of 85 patients were included. The median follow-up was 15 years. The 20-year overall survival (OS) and relapse free survival (RFS) were 92% and 96.3%, respectively. No severe acute and late complications were recorded. Overall 5.9% of patients had a second unrelated malignancy. CONCLUSION: Adjuvant RT is an efficacious and safe treatment in stage I seminoma. Impact Journals LLC 2016-08-18 /pmc/articles/PMC5346772/ /pubmed/27556300 http://dx.doi.org/10.18632/oncotarget.11374 Text en Copyright: © 2016 Felice et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Clinical Research Paper
De Felice, Francesca
Musio, Daniela
Gravina, Giovanni Luca
Marampon, Francesco
Tombolini, Vincenzo
Adjuvant radiation therapy in stage I seminoma: 20 years of oncologic results
title Adjuvant radiation therapy in stage I seminoma: 20 years of oncologic results
title_full Adjuvant radiation therapy in stage I seminoma: 20 years of oncologic results
title_fullStr Adjuvant radiation therapy in stage I seminoma: 20 years of oncologic results
title_full_unstemmed Adjuvant radiation therapy in stage I seminoma: 20 years of oncologic results
title_short Adjuvant radiation therapy in stage I seminoma: 20 years of oncologic results
title_sort adjuvant radiation therapy in stage i seminoma: 20 years of oncologic results
topic Clinical Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346772/
https://www.ncbi.nlm.nih.gov/pubmed/27556300
http://dx.doi.org/10.18632/oncotarget.11374
work_keys_str_mv AT defelicefrancesca adjuvantradiationtherapyinstageiseminoma20yearsofoncologicresults
AT musiodaniela adjuvantradiationtherapyinstageiseminoma20yearsofoncologicresults
AT gravinagiovanniluca adjuvantradiationtherapyinstageiseminoma20yearsofoncologicresults
AT maramponfrancesco adjuvantradiationtherapyinstageiseminoma20yearsofoncologicresults
AT tombolinivincenzo adjuvantradiationtherapyinstageiseminoma20yearsofoncologicresults

Ejemplares similares