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Aptamer-based sandwich-type biosensors
Sandwich-type biosensor platforms have drawn lots of attentions due to its superior features, compared to other platforms, in terms of its stable and reproducible responses and easy enhancement in the detection sensitivity. The sandwich-type assays can be developed by utilizing a pair of receptors,...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346835/ https://www.ncbi.nlm.nih.gov/pubmed/28293287 http://dx.doi.org/10.1186/s13036-017-0054-7 |
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author | Seo, Ho Bin Gu, Man Bock |
author_facet | Seo, Ho Bin Gu, Man Bock |
author_sort | Seo, Ho Bin |
collection | PubMed |
description | Sandwich-type biosensor platforms have drawn lots of attentions due to its superior features, compared to other platforms, in terms of its stable and reproducible responses and easy enhancement in the detection sensitivity. The sandwich-type assays can be developed by utilizing a pair of receptors, which bind to the different sites of the same target. In this mini-review paper, the sandwich-type biosensors using either pairs of aptamers or aptamer-antibody pairs are reviewed in terms of its targets and platforms, the schematic designs, and their analytical performance. |
format | Online Article Text |
id | pubmed-5346835 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-53468352017-03-14 Aptamer-based sandwich-type biosensors Seo, Ho Bin Gu, Man Bock J Biol Eng Review Sandwich-type biosensor platforms have drawn lots of attentions due to its superior features, compared to other platforms, in terms of its stable and reproducible responses and easy enhancement in the detection sensitivity. The sandwich-type assays can be developed by utilizing a pair of receptors, which bind to the different sites of the same target. In this mini-review paper, the sandwich-type biosensors using either pairs of aptamers or aptamer-antibody pairs are reviewed in terms of its targets and platforms, the schematic designs, and their analytical performance. BioMed Central 2017-03-13 /pmc/articles/PMC5346835/ /pubmed/28293287 http://dx.doi.org/10.1186/s13036-017-0054-7 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Review Seo, Ho Bin Gu, Man Bock Aptamer-based sandwich-type biosensors |
title | Aptamer-based sandwich-type biosensors |
title_full | Aptamer-based sandwich-type biosensors |
title_fullStr | Aptamer-based sandwich-type biosensors |
title_full_unstemmed | Aptamer-based sandwich-type biosensors |
title_short | Aptamer-based sandwich-type biosensors |
title_sort | aptamer-based sandwich-type biosensors |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346835/ https://www.ncbi.nlm.nih.gov/pubmed/28293287 http://dx.doi.org/10.1186/s13036-017-0054-7 |
work_keys_str_mv | AT seohobin aptamerbasedsandwichtypebiosensors AT gumanbock aptamerbasedsandwichtypebiosensors |