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The inflammatory cytokine effect of Pam3CSK4 TLR2 agonist alone or in combination with Leishmania infantum antigen on ex-vivo whole blood from sick and resistant dogs

BACKGROUND: A wide spectrum of clinical manifestations and immune responses exist in canine L. infantum infection. Ibizan hounds are more “resistant” to disease than other dog breeds. Recognition of pathogen-associated molecule patterns by toll like receptors (TLRs) rapidly triggers a variety of ant...

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Detalles Bibliográficos
Autores principales:	Martínez-Orellana, Pamela, Quirola-Amores, Paulina, Montserrat-Sangrà, Sara, Ordeix, Laura, Llull, Joan, Álvarez-Fernández, Alejandra, Solano-Gallego, Laia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346840/ https://www.ncbi.nlm.nih.gov/pubmed/28288677 http://dx.doi.org/10.1186/s13071-017-2062-3

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