Autonomic Dysregulation, Cognitive Impairment, and Symptoms of Psychosis as an Unusual Presentation in an Anti-Aquaporin 4-Positive Patient

We present the unusual case of a patient with an aquaporin 4 antibody-seropositive neuromyelitis optica spectrum disorder who presented with autonomic dysregulation, cognitive impairment, and symptoms of psychosis. Only a few previous cases have been described with similar psychiatric symptoms. Brai...

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Autores principales: Ruiter, Annabel M., Meilof, Jan F., Somanje-Bolweg, Rosemarijn R.J., van Gorsel, Erik, Kalkers, Nynke F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346915/
https://www.ncbi.nlm.nih.gov/pubmed/28413400
http://dx.doi.org/10.1159/000455942
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author Ruiter, Annabel M.
Meilof, Jan F.
Somanje-Bolweg, Rosemarijn R.J.
van Gorsel, Erik
Kalkers, Nynke F.
author_facet Ruiter, Annabel M.
Meilof, Jan F.
Somanje-Bolweg, Rosemarijn R.J.
van Gorsel, Erik
Kalkers, Nynke F.
author_sort Ruiter, Annabel M.
collection PubMed
description We present the unusual case of a patient with an aquaporin 4 antibody-seropositive neuromyelitis optica spectrum disorder who presented with autonomic dysregulation, cognitive impairment, and symptoms of psychosis. Only a few previous cases have been described with similar psychiatric symptoms. Brain MRI showed an abnormal hyperintense T2 signal of the hypothalamus and, to a lesser extent, a minor hyperintense signal of the right optic nerve. Her symptoms and MR abnormalities improved after high-dose methylprednisolone.
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spelling pubmed-53469152017-04-14 Autonomic Dysregulation, Cognitive Impairment, and Symptoms of Psychosis as an Unusual Presentation in an Anti-Aquaporin 4-Positive Patient Ruiter, Annabel M. Meilof, Jan F. Somanje-Bolweg, Rosemarijn R.J. van Gorsel, Erik Kalkers, Nynke F. Case Rep Neurol Case Report We present the unusual case of a patient with an aquaporin 4 antibody-seropositive neuromyelitis optica spectrum disorder who presented with autonomic dysregulation, cognitive impairment, and symptoms of psychosis. Only a few previous cases have been described with similar psychiatric symptoms. Brain MRI showed an abnormal hyperintense T2 signal of the hypothalamus and, to a lesser extent, a minor hyperintense signal of the right optic nerve. Her symptoms and MR abnormalities improved after high-dose methylprednisolone. S. Karger AG 2017-02-06 /pmc/articles/PMC5346915/ /pubmed/28413400 http://dx.doi.org/10.1159/000455942 Text en Copyright © 2017 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Ruiter, Annabel M.
Meilof, Jan F.
Somanje-Bolweg, Rosemarijn R.J.
van Gorsel, Erik
Kalkers, Nynke F.
Autonomic Dysregulation, Cognitive Impairment, and Symptoms of Psychosis as an Unusual Presentation in an Anti-Aquaporin 4-Positive Patient
title Autonomic Dysregulation, Cognitive Impairment, and Symptoms of Psychosis as an Unusual Presentation in an Anti-Aquaporin 4-Positive Patient
title_full Autonomic Dysregulation, Cognitive Impairment, and Symptoms of Psychosis as an Unusual Presentation in an Anti-Aquaporin 4-Positive Patient
title_fullStr Autonomic Dysregulation, Cognitive Impairment, and Symptoms of Psychosis as an Unusual Presentation in an Anti-Aquaporin 4-Positive Patient
title_full_unstemmed Autonomic Dysregulation, Cognitive Impairment, and Symptoms of Psychosis as an Unusual Presentation in an Anti-Aquaporin 4-Positive Patient
title_short Autonomic Dysregulation, Cognitive Impairment, and Symptoms of Psychosis as an Unusual Presentation in an Anti-Aquaporin 4-Positive Patient
title_sort autonomic dysregulation, cognitive impairment, and symptoms of psychosis as an unusual presentation in an anti-aquaporin 4-positive patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346915/
https://www.ncbi.nlm.nih.gov/pubmed/28413400
http://dx.doi.org/10.1159/000455942
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