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A Bacterial Artificial Chromosome Reporter System for Expression of the Human FOXP3 Gene in Mouse Regulatory T-Cells

The transcription factor FOXP3 plays key roles in the development and function of regulatory T cells (Treg) capable of preventing and correcting immunopathology. There has been much interest in exploiting Treg as adoptive cell therapy in man, but issues of lack of nominal antigen-specificity and sta...

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Detalles Bibliográficos
Autores principales: Tsuda, Masato, Tone, Yukiko, Ogawa, Chihiro, Nagaoka, Yoshiko, Katsumata, Makoto, Necula, Andra, Howie, Duncan, Masuda, Esteban, Waldmann, Herman, Tone, Masahide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346934/
https://www.ncbi.nlm.nih.gov/pubmed/28348568
http://dx.doi.org/10.3389/fimmu.2017.00279