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Enhanced osteogenesis and angiogenesis by mesoporous hydroxyapatite microspheres-derived simvastatin sustained release system for superior bone regeneration
Biomaterials with both excellent osteogenic and angiogenic activities are desirable to repair massive bone defects. In this study, simvastatin with both osteogenic and angiogenic activities was incorporated into the mesoporous hydroxyapatite microspheres (MHMs) synthesized through a microwave-assist...
Autores principales: | Yu, Wei-Lin, Sun, Tuan-Wei, Qi, Chao, Zhao, Hua-Kun, Ding, Zhen-Yu, Zhang, Zhi-Wang, Sun, Ben-Ben, Shen, Ji, Chen, Feng, Zhu, Ying-Jie, Chen, Dao-Yun, He, Yao-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347005/ https://www.ncbi.nlm.nih.gov/pubmed/28287178 http://dx.doi.org/10.1038/srep44129 |
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