HDL Glycoprotein Composition and Site-Specific Glycosylation Differentiates Between Clinical Groups and Affects IL-6 Secretion in Lipopolysaccharide-Stimulated Monocytes

The goal of this pilot study was to determine whether HDL glycoprotein composition affects HDL’s immunomodulatory function. HDL were purified from healthy controls (n = 13), subjects with metabolic syndrome (MetS) (n = 13), and diabetic hemodialysis (HD) patients (n = 24). Concentrations of HDL-boun...

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Detalles Bibliográficos
Autores principales: Krishnan, Sridevi, Shimoda, Michiko, Sacchi, Romina, Kailemia, Muchena J., Luxardi, Guillaume, Kaysen, George A., Parikh, Atul N., Ngassam, Viviane N., Johansen, Kirsten, Chertow, Glenn M., Grimes, Barbara, Smilowitz, Jennifer T., Maverakis, Emanual, Lebrilla, Carlito B., Zivkovic, Angela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347119/
https://www.ncbi.nlm.nih.gov/pubmed/28287093
http://dx.doi.org/10.1038/srep43728

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