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NLRX1 accelerates cisplatin-induced ototoxity in HEI-OC1 cells via promoting generation of ROS and activation of JNK signaling pathway

Nucleotide-binding domain and leucine-rich-repeat-containing family member X1 (NLRX1), located in mitochondria, can recognize cytoplasmic pattern recognition receptors and is tightly related to reactive oxygen species (ROS) production, mitochondrial function, apoptosis and inflammation. The present...

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Detalles Bibliográficos
Autores principales:	Yin, Haiyan, Sun, Gaoying, Yang, Qianqian, Chen, Chen, Qi, Qi, Wang, Haibo, Li, Jianfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347132/ https://www.ncbi.nlm.nih.gov/pubmed/28287190 http://dx.doi.org/10.1038/srep44311

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