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Persistent Symblepharon in an Infant Following Epidemic Keratoconjunctivitis

Epidemic keratoconjunctivitis (EKC), caused by certain species D human adenoviruses (Ads), is a highly contagious severe disease involving both the conjunctiva and cornea. The hallmark of this disease is the subepithelial infiltration of leukocytes, which results in corneal opacities that may persis...

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Autores principales: AKKAYA, Sezen, OZKURT, Yelda Buyru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medical Hypothesis, Discovery & Innovation Ophthalmology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347208/
https://www.ncbi.nlm.nih.gov/pubmed/28293652
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author AKKAYA, Sezen
OZKURT, Yelda Buyru
author_facet AKKAYA, Sezen
OZKURT, Yelda Buyru
author_sort AKKAYA, Sezen
collection PubMed
description Epidemic keratoconjunctivitis (EKC), caused by certain species D human adenoviruses (Ads), is a highly contagious severe disease involving both the conjunctiva and cornea. The hallmark of this disease is the subepithelial infiltration of leukocytes, which results in corneal opacities that may persist for months or even years. In this case, of a 6-month-old infant, we report a symblepharon formation, a relatively rare outcome of EKC. In this condition, the palpebral conjunctiva adheres tightly to the bulbar conjunctiva of the eyeball. Our report is the first documentation of a symblepharon formation in an infant. Only two similar cases have been reported to date; therefore, a detailed description is of considerable interest to ophthalmologists. This is particularly interesting since a previous publication has associated symblepharon formation with an adenovirus infection, which is not usually involved in EKC. The development of a symblepharon following EKC is rare in infants. Since topical treatment cannot be applied due to severe eyelid edema, oral steroid therapy can be administered with pediatric consultation and meticulous monitoring.
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spelling pubmed-53472082017-03-14 Persistent Symblepharon in an Infant Following Epidemic Keratoconjunctivitis AKKAYA, Sezen OZKURT, Yelda Buyru Med Hypothesis Discov Innov Ophthalmol Case Report Epidemic keratoconjunctivitis (EKC), caused by certain species D human adenoviruses (Ads), is a highly contagious severe disease involving both the conjunctiva and cornea. The hallmark of this disease is the subepithelial infiltration of leukocytes, which results in corneal opacities that may persist for months or even years. In this case, of a 6-month-old infant, we report a symblepharon formation, a relatively rare outcome of EKC. In this condition, the palpebral conjunctiva adheres tightly to the bulbar conjunctiva of the eyeball. Our report is the first documentation of a symblepharon formation in an infant. Only two similar cases have been reported to date; therefore, a detailed description is of considerable interest to ophthalmologists. This is particularly interesting since a previous publication has associated symblepharon formation with an adenovirus infection, which is not usually involved in EKC. The development of a symblepharon following EKC is rare in infants. Since topical treatment cannot be applied due to severe eyelid edema, oral steroid therapy can be administered with pediatric consultation and meticulous monitoring. Medical Hypothesis, Discovery & Innovation Ophthalmology 2016 /pmc/articles/PMC5347208/ /pubmed/28293652 Text en ©2016, Med Hypothesis Discov Innov Ophthalmol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
AKKAYA, Sezen
OZKURT, Yelda Buyru
Persistent Symblepharon in an Infant Following Epidemic Keratoconjunctivitis
title Persistent Symblepharon in an Infant Following Epidemic Keratoconjunctivitis
title_full Persistent Symblepharon in an Infant Following Epidemic Keratoconjunctivitis
title_fullStr Persistent Symblepharon in an Infant Following Epidemic Keratoconjunctivitis
title_full_unstemmed Persistent Symblepharon in an Infant Following Epidemic Keratoconjunctivitis
title_short Persistent Symblepharon in an Infant Following Epidemic Keratoconjunctivitis
title_sort persistent symblepharon in an infant following epidemic keratoconjunctivitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347208/
https://www.ncbi.nlm.nih.gov/pubmed/28293652
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