Differential Antibody Responses to Conserved HIV-1 Neutralizing Epitopes in the Context of Multivalent Scaffolds and Native-Like gp140 Trimers

Broadly neutralizing antibodies (bNAbs) have provided valuable insights into the humoral immune response to HIV-1. While rationally designed epitope scaffolds and well-folded gp140 trimers have been proposed as vaccine antigens, a comparative understanding of their antibody responses has not yet bee...

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Detalles Bibliográficos
Autores principales: Morris, Charles D., Azadnia, Parisa, de Val, Natalia, Vora, Nemil, Honda, Andrew, Giang, Erick, Saye-Francisco, Karen, Cheng, Yushao, Lin, Xiaohe, Mann, Colin J., Tang, Jeffrey, Sok, Devin, Burton, Dennis R., Law, Mansun, Ward, Andrew B., He, Linling, Zhu, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347340/
https://www.ncbi.nlm.nih.gov/pubmed/28246356
http://dx.doi.org/10.1128/mBio.00036-17

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