Toxoplasma DJ-1 Regulates Organelle Secretion by a Direct Interaction with Calcium-Dependent Protein Kinase 1

Human DJ-1 is a highly conserved and yet functionally enigmatic protein associated with a heritable form of Parkinson’s disease. It has been suggested to be a redox-dependent regulatory scaffold, binding to proteins to modulate their function. Here we present the X-ray crystal structure of the Toxop...

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Detalles Bibliográficos
Autores principales: Child, Matthew A., Garland, Megan, Foe, Ian, Madzelan, Peter, Treeck, Moritz, van der Linden, Wouter A., Oresic Bender, Kristina, Weerapana, Eranthie, Wilson, Mark A., Boothroyd, John C., Reese, Michael L., Bogyo, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347346/
https://www.ncbi.nlm.nih.gov/pubmed/28246362
http://dx.doi.org/10.1128/mBio.02189-16

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