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Elevated Cholesterol in the Coxiella burnetii Intracellular Niche Is Bacteriolytic
Coxiella burnetii is an intracellular bacterial pathogen and a significant cause of culture-negative endocarditis in the United States. Upon infection, the nascent Coxiella phagosome fuses with the host endocytic pathway to form a large lysosome-like vacuole called the parasitophorous vacuole (PV)....
Autores principales: | Mulye, Minal, Samanta, Dhritiman, Winfree, Seth, Heinzen, Robert A., Gilk, Stacey D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347348/ https://www.ncbi.nlm.nih.gov/pubmed/28246364 http://dx.doi.org/10.1128/mBio.02313-16 |
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