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graph-GPA: A graphical model for prioritizing GWAS results and investigating pleiotropic architecture

Genome-wide association studies (GWAS) have identified tens of thousands of genetic variants associated with hundreds of phenotypes and diseases, which have provided clinical and medical benefits to patients with novel biomarkers and therapeutic targets. However, identification of risk variants asso...

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Detalles Bibliográficos
Autores principales: Chung, Dongjun, Kim, Hang J., Zhao, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347371/
https://www.ncbi.nlm.nih.gov/pubmed/28212402
http://dx.doi.org/10.1371/journal.pcbi.1005388