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Pitfalls and artifacts in the interpretation of oncologic PET/CT of the chest

PET/CT is widely used for the evaluation of patients with thoracic malignancies. Although the levels of (18)F-fluorodeoxyglucose (FDG) uptake are usually high in neoplastic diseases, they can also be physiological, due to artifacts. In addition, FDG uptake can occur in benign conditions such as infe...

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Detalles Bibliográficos
Autores principales: Meirelles, Gustavo de Souza Portes, Capobianco, Julia, de Oliveira, Marco Antônio Condé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Colégio Brasileiro de Radiologia e Diagnóstico por Imagem 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347504/
https://www.ncbi.nlm.nih.gov/pubmed/28298733
http://dx.doi.org/10.1590/0100-3984.2015.0194
Descripción
Sumario:PET/CT is widely used for the evaluation of patients with thoracic malignancies. Although the levels of (18)F-fluorodeoxyglucose (FDG) uptake are usually high in neoplastic diseases, they can also be physiological, due to artifacts. In addition, FDG uptake can occur in benign conditions such as infectious, inflammatory, and iatrogenic lesions. Furthermore, some malignant tumors, such as adenocarcinoma in situ (formerly known as bronchoalveolar carcinoma) and carcinoid tumors, may not show FDG uptake. Here, we illustrate the main pitfalls and artifacts in the interpretation of the results of oncologic PET/CT of the chest, outlining strategies for avoiding misinterpretation.