Serpin E2 promotes breast cancer metastasis by remodeling the tumor matrix and polarizing tumor associated macrophages

The extracellular serine protease inhibitor serpinE2 is overexpressed in breast cancer and has been shown to foster metastatic spread. Here, we investigated the hypothesis that serpinE2 creates tumor-promoting conditions in the tumor microenvironment (TME) by affecting extracellular matrix remodelin...

Descripción completa

Detalles Bibliográficos
Autores principales: Smirnova, Tatiana, Bonapace, Laura, MacDonald, Gwen, Kondo, Shunya, Wyckoff, Jeffrey, Ebersbach, Hilmar, Fayard, Bérengère, Doelemeyer, Arno, Coissieux, Marie-May, Heideman, Marinus R., Bentires-Alj, Mohamed, Hynes, Nancy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347692/
https://www.ncbi.nlm.nih.gov/pubmed/27793045
http://dx.doi.org/10.18632/oncotarget.12927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347692/
https://www.ncbi.nlm.nih.gov/pubmed/27793045
http://dx.doi.org/10.18632/oncotarget.12927

Ejemplares similares