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ATM is the primary kinase responsible for phosphorylation of Hsp90α after ionizing radiation

Heat shock protein 90 is a chaperone that plays an essential role in the stabilization of a large number of signal transduction molecules, many of which are associated with oncogenesis. An Hsp90 isoform (Hsp90α) has been shown to be selectively phosphorylated on two N-terminal threonine residues (th...

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Detalles Bibliográficos
Autores principales: Elaimy, Ameer L., Ahsan, Aarif, Marsh, Katherine, Pratt, William B., Ray, Dipankar, Lawrence, Theodore S., Nyati, Mukesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347704/
https://www.ncbi.nlm.nih.gov/pubmed/27738310
http://dx.doi.org/10.18632/oncotarget.12557