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Mesenchymal stem cells and macrophages interact through IL-6 to promote inflammatory breast cancer in pre-clinical models
Inflammatory breast cancer (IBC) is a unique and deadly disease with unknown drivers. We hypothesized the inflammatory environment contributes to the IBC phenotype. We used an in vitro co-culture system to investigate interactions between normal and polarized macrophages (RAW 264.7 cell line), bone-...
Autores principales: | Wolfe, Adam R., Trenton, Nicholaus J, Debeb, Bisrat G., Larson, Richard, Ruffell, Brian, Chu, Khoi, Hittelman, Walter, Diehl, Michael, Reuben, Jim M, Ueno, Naoto T., Woodward, Wendy A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347707/ https://www.ncbi.nlm.nih.gov/pubmed/27756885 http://dx.doi.org/10.18632/oncotarget.12694 |
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