ALK FISH patterns and the detection of ALK fusions by next generation sequencing in lung adenocarcinoma

Break-apart ALK FISH probe is the FDA approved approach for detection of ALK rearrangements in lung carcinoma patients who may benefit from ALK kinase inhibitors. The FISH assay can be technically challenging and difficult to interpret. ALK immunohistochemistry and next generation sequencing have be...

Descripción completa

Detalles Bibliográficos
Autores principales: Dacic, Sanja, Villaruz, Liza C., Abberbock, Shira, Mahaffey, Alyssa, Incharoen, Pimpin, Nikiforova, Marina N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347743/
https://www.ncbi.nlm.nih.gov/pubmed/27769042
http://dx.doi.org/10.18632/oncotarget.12705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347743/
https://www.ncbi.nlm.nih.gov/pubmed/27769042
http://dx.doi.org/10.18632/oncotarget.12705

Ejemplares similares