ERN1 and ALPK1 inhibit differentiation of bi-potential tumor-initiating cells in human breast cancer

Cancers are heterogeneous by nature. While traditional oncology screens commonly use a single endpoint of cell viability, altering the phenotype of tumor-initiating cells may reveal alternative targets that regulate cellular growth by processes other than apoptosis or cell division. We evaluated the...

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Detalles Bibliográficos
Autores principales: Strietz, Juliane, Stepputtis, Stella S., Preca, Bogdan-Tiberius, Vannier, Corinne, Kim, Mihee M., Castro, David J., Au, Qingyan, Boerries, Melanie, Busch, Hauke, Aza-Blanc, Pedro, Heynen-Genel, Susanne, Bronsert, Peter, Kuster, Bernhard, Stickeler, Elmar, Brabletz, Thomas, Oshima, Robert G., Maurer, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347769/
https://www.ncbi.nlm.nih.gov/pubmed/27829216
http://dx.doi.org/10.18632/oncotarget.13086

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