Gene expression profile induced by arsenic trioxide in chronic lymphocytic leukemia cells reveals a central role for heme oxygenase-1 in apoptosis and regulation of matrix metalloproteinase-9

CLL remains an incurable disease in spite of the many new compounds being tested. Arsenic trioxide (ATO) induces apoptosis in all CLL cell types and could constitute an efficient therapy. To further explore this, we have studied the gene expression profile induced by ATO in CLL cells. ATO modulated...

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Detalles Bibliográficos
Autores principales: Amigo-Jiménez, Irene, Bailón, Elvira, Aguilera-Montilla, Noemí, García-Marco, José A., García-Pardo, Angeles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347775/
https://www.ncbi.nlm.nih.gov/pubmed/27829220
http://dx.doi.org/10.18632/oncotarget.13091

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