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Bisdemethoxycurcumin exerts pro-apoptotic effects in human pancreatic adenocarcinoma cells through mitochondrial dysfunction and a GRP78-dependent pathway

Pancreatic cancer is a highly aggressive malignancy, which is intrinsically resistant to current chemotherapies. Herein, we investigate whether bisdemethoxycurcumin (BDMC), a derivative of curcumin, potentiates gemcitabine in human pancreatic cancer cells. The result suggests that BDMC sensitizes ge...

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Detalles Bibliográficos
Autores principales:	Yang, Haopeng, Fan, Shengjun, An, Yu, Wang, Xin, Pan, Yan, Xiaokaiti, Yilixiati, Duan, Jianhui, Li, Xin, Tie, Lu, Ye, Min, Li, Xuejun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347794/ https://www.ncbi.nlm.nih.gov/pubmed/27845899 http://dx.doi.org/10.18632/oncotarget.13272

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