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Platelet derived growth factor receptor alpha mediates nodal metastases in papillary thyroid cancer by driving the epithelial-mesenchymal transition

Recently platelet derived growth factor receptor-alpha (PDGFRα) was recognized as a potential target to treat aggressive papillary thyroid cancer given its strong association with lymph node metastases. However, it is unclear how PDGFRα potentiates metastases and if it works through the canonical MA...

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Detalles Bibliográficos
Autores principales:	Ekpe-Adewuyi, Esther, Lopez-Campistrous, Ana, Tang, Xiaoyun, Brindley, David N., McMullen, Todd P. W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347797/ https://www.ncbi.nlm.nih.gov/pubmed/27845909 http://dx.doi.org/10.18632/oncotarget.13299

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