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Protein Surface Mimetics: Understanding How Ruthenium Tris(Bipyridines) Interact with Proteins

Protein surface mimetics achieve high‐affinity binding by exploiting a scaffold to project binding groups over a large area of solvent‐exposed protein surface to make multiple cooperative noncovalent interactions. Such recognition is a prerequisite for competitive/orthosteric inhibition of protein–p...

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Detalles Bibliográficos
Autores principales:	Hewitt, Sarah H., Filby, Maria H., Hayes, Ed, Kuhn, Lars T., Kalverda, Arnout P., Webb, Michael E., Wilson, Andrew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347857/ https://www.ncbi.nlm.nih.gov/pubmed/27860106 http://dx.doi.org/10.1002/cbic.201600552

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