Bistable Epigenetic States Explain Age‐Dependent Decline in Mesenchymal Stem Cell Heterogeneity

The molecular mechanisms by which heterogeneity, a major characteristic of stem cells, is achieved are yet unclear. We here study the expression of the membrane stem cell antigen‐1 (Sca‐1) in mouse bone marrow mesenchymal stem cell (MSC) clones. We show that subpopulations with varying Sca‐1 express...

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Detalles Bibliográficos
Autores principales: Hamidouche, Zahia, Rother, Karen, Przybilla, Jens, Krinner, Axel, Clay, Denis, Hopp, Lydia, Fabian, Claire, Stolzing, Alexandra, Binder, Hans, Charbord, Pierre, Galle, Joerg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Tissue‐Specific Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347872/
https://www.ncbi.nlm.nih.gov/pubmed/27734598
http://dx.doi.org/10.1002/stem.2514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347872/
https://www.ncbi.nlm.nih.gov/pubmed/27734598
http://dx.doi.org/10.1002/stem.2514

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