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Prolonged Integration Site Selection of a Lentiviral Vector in the Genome of Human Keratinocytes

BACKGROUND: Lentiviral vectors have been successfully used for human skin cell gene transfer studies. Defining the selection of integration sites for retroviral vectors in the host genome is crucial in risk assessment analysis of gene therapy. However, genome-wide analyses of lentiviral integration...

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Detalles Bibliográficos
Autores principales:	Qian, Wei, Wang, Yong, Li, Rui-fu, Zhou, Xin, Liu, Jing, Peng, Dai-zhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2017
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5347986/ https://www.ncbi.nlm.nih.gov/pubmed/28255155 http://dx.doi.org/10.12659/MSM.903094

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