Pleiotrophin enhances PDGFB-induced gliomagenesis through increased proliferation of neural progenitor cells

Pleiotrophin (PTN) augments tumor growth by increasing proliferation of tumor cells and promoting vascular abnormalization, but its role in early gliomagenesis has not been evaluated. Through analysis of publically available datasets, we demonstrate that increased PTN mRNA expression is associated w...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Laaniste, Liisi, Jiang, Yiwen, Alafuzoff, Irina, Uhrbom, Lene, Dimberg, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348327/
https://www.ncbi.nlm.nih.gov/pubmed/27806344
http://dx.doi.org/10.18632/oncotarget.12983

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