A role for the vitamin D pathway in non-intestinal lesions in genetic and carcinogen models of colorectal cancer and in familial adenomatous polyposis

Vitamin D is implicated in the etiology of cancers of the gastrointestinal tract, usually characterized by alteration in the APC/β-catenin/TCF tumor suppressor pathway. The vitamin D receptor (VDR) is also implicated in cardiovascular and skin diseases as well as in immunity. Activated VDR can indir...

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Detalles Bibliográficos
Autores principales: Bong, Yong-Sik, Assefnia, Shahin, Tuohy, Therese, Neklason, Deborah W, Burt, Randall W, Ahn, Jaeil, De Mesquita, Paul J Bueno, Byers, Stephen W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348337/
https://www.ncbi.nlm.nih.gov/pubmed/27768599
http://dx.doi.org/10.18632/oncotarget.12768

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