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The induction of autophagy against mitochondria-mediated apoptosis in lung cancer cells by a ruthenium (II) imidazole complex
In the present study, it was found that the ruthenium (II) imidazole complex [Ru(Im)(4)(dppz)](2+) (Ru1) could induce significant growth inhibition and apoptosis in A549 and NCI-H460 cells. Apart from the induction of apoptosis, it was reported for the first time that Ru1 induced an autophagic respo...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348350/ https://www.ncbi.nlm.nih.gov/pubmed/27811372 http://dx.doi.org/10.18632/oncotarget.13032 |