The induction of autophagy against mitochondria-mediated apoptosis in lung cancer cells by a ruthenium (II) imidazole complex

In the present study, it was found that the ruthenium (II) imidazole complex [Ru(Im)(4)(dppz)](2+) (Ru1) could induce significant growth inhibition and apoptosis in A549 and NCI-H460 cells. Apart from the induction of apoptosis, it was reported for the first time that Ru1 induced an autophagic respo...

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Detalles Bibliográficos
Autores principales: Chen, Lanmei, Li, Guodong, Peng, Fa, Jie, Xinming, Dongye, Guangzhi, Cai, Kangrong, Feng, Ruibing, Li, Baojun, Zeng, Qingwang, Lun, Kaiyi, Chen, Jincan, Xu, Bilian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348350/
https://www.ncbi.nlm.nih.gov/pubmed/27811372
http://dx.doi.org/10.18632/oncotarget.13032

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