Activation of PI3Kγ/Akt pathway increases cardiomyocyte HMGB1 expression in diabetic environment

BACKGROUND: The high mobility group box 1 (HMGB1) protein mediates the cardiomyocyte–cardiac fibroblast interaction that contributes to induction of myocardial fibrosis in diabetes mellitus (DM). In the present study, we aim to investigate the intracellular signaling pathway that leads to cardiomyoc...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Jia, Liu, Qian, Tang, Han, Tao, Aibin, Wang, Hao, Kao, Raymond, Rui, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348356/
https://www.ncbi.nlm.nih.gov/pubmed/27821807
http://dx.doi.org/10.18632/oncotarget.13096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348356/
https://www.ncbi.nlm.nih.gov/pubmed/27821807
http://dx.doi.org/10.18632/oncotarget.13096

Ejemplares similares