RNAi screens identify CHD4 as an essential gene in breast cancer growth

Epigenetic regulation plays an essential role in tumor development and epigenetic modifiers are considered optimal potential druggable candidates. In order to identify new breast cancer vulnerabilities and improve therapeutic chances for patients, we performed in vivo and in vitro shRNA screens in a...

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Detalles Bibliográficos
Autores principales: D'Alesio, Carolina, Punzi, Simona, Cicalese, Angelo, Fornasari, Lorenzo, Furia, Laura, Riva, Laura, Carugo, Alessandro, Curigliano, Giuseppe, Criscitiello, Carmen, Pruneri, Giancarlo, Pelicci, Pier Giuseppe, Faretta, Mario, Bossi, Daniela, Lanfrancone, Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348363/
https://www.ncbi.nlm.nih.gov/pubmed/27779108
http://dx.doi.org/10.18632/oncotarget.12646

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