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Deregulation of small non-coding RNAs at the DLK1-DIO3 imprinted locus predicts lung cancer patient outcome

Deregulation of the imprinted DLK1-DIO3 locus at chromosome 14q32.1-14q32.31 has been associated with developmental and respiratory disorders, including cancer. In lung cancer, deregulation of imprinting at DLK1-DIO3 was recently described in smokers. Deregulated expression of a microRNA (miRNA) clu...

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Detalles Bibliográficos
Autores principales: Enfield, Katey S.S., Martinez, Victor D., Marshall, Erin A., Stewart, Greg L., Kung, Sonia H.Y., Enterina, Jhon R., Lam, Wan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348368/
https://www.ncbi.nlm.nih.gov/pubmed/27829231
http://dx.doi.org/10.18632/oncotarget.13133