Preclinical evaluation of the safety and pathogenicity of a live attenuated recombinant influenza A/H7N9 seed strain and corresponding MF59-adjuvanted split vaccine

Developing a safe and effective H7N9 influenza vaccine was initiated in early spring 2013, following human infections with a novel avian influenza A (H7N9) virus. In this study, a candidate H7N9 vaccine seed strain is produced using reverse genetics, with HA and NA derived from a human H7N9 virus an...

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Detalles Bibliográficos
Autores principales: Ou, Huilin, Yao, Wei, Wu, Nanping, Wang, Frederick X.C., Weng, Tianhao, Han, Chengcong, Lu, Xiangyun, Yu, Dongshan, Wu, Haibo, Cheng, Linfang, Chen, Honglin, Yao, Hangping, Li, Lanjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348373/
https://www.ncbi.nlm.nih.gov/pubmed/27768591
http://dx.doi.org/10.18632/oncotarget.12746

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