Inhibiting tumor necrosis factor-alpha diminishes desmoplasia and inflammation to overcome chemoresistance in pancreatic ductal adenocarcinoma

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is one of the most common cancer death reasons. Anti-tumor necrosis factor-alpha (TNF-α) antibodies have shown promising effects in PDAC pre-clinical models. However, the prognostic values of TNF-α, underlying mechanisms by which anti-TNF-α treatme...

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Detalles Bibliográficos
Autores principales: Zhao, Xianda, Fan, Wei, Xu, Zhigao, Chen, Honglei, He, Yuyu, Yang, Gui, Yang, Gang, Hu, Hanning, Tang, Shihui, Wang, Ping, Zhang, Zheng, Xu, Peipei, Yu, Mingxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348380/
https://www.ncbi.nlm.nih.gov/pubmed/27835602
http://dx.doi.org/10.18632/oncotarget.13212

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