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Gankyrin sustains PI3K/GSK-3β/β-catenin signal activation and promotes colorectal cancer aggressiveness and progression
High levels of angiogenesis, metastasis and chemoresistance are major clinical features of colorectal cancer (CRC), a lethal disease with a high incidence worldwide. Aberrant activation of Wnt/β-catenin pathway contributes to CRC progression. However, little is known about regulatory mechanisms of t...
Autores principales: | He, Feng, Chen, Huacui, Yang, Ping, Wu, Qianlong, Zhang, Tong, Wang, Chengxing, Wei, Jianchang, Chen, Zhuanpeng, Hu, He, Li, Wanglin, Cao, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348383/ https://www.ncbi.nlm.nih.gov/pubmed/27835604 http://dx.doi.org/10.18632/oncotarget.13215 |
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