Cargando…

Determining the optimal 5-FU therapeutic dosage in the treatment of colorectal cancer patients

Fluorouracil (5-FU) has been wildly used as a primary medication in the treatment of solid tumors including colorectal cancer. The treatment efficacy and toxicity of 5-FU varies greatly among individuals, suggesting a need for individualized regimen for cancer patients. The present study analyzed th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fang, Ling, Jiang, Yi, Yang, Yuxian, Zheng, Yuqiong, Zheng, Jin, Jiang, Hong, Zhang, Shengqi, Lin, Lifang, Zheng, Jieting, Zhang, Shuyao, Zhuang, Xiaowen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Clinical Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348438/ https://www.ncbi.nlm.nih.gov/pubmed/27636992 http://dx.doi.org/10.18632/oncotarget.11980

Ejemplares similares

Combined Therapeutic Effects of (131)I-Labeled and 5Fu-Loaded Multifunctional Nanoparticles in Colorectal Cancer
por: Wu, Pingping, et al.
Publicado: (2020)

Neglected, Drug-Induced Platinum Accumulation Causes Immune Toxicity
por: Zhang, Yuling, et al.
Publicado: (2020)

GDC-0326 Enhances the Effects of 5-Fu in Colorectal Cancer Cells by Inducing Necroptotic Death
por: Zhang, Zizhen, et al.
Publicado: (2021)

Aspirin suppresses chemoresistance and enhances antitumor activity of 5-Fu in 5-Fu-resistant colorectal cancer by abolishing 5-Fu-induced NF-κB activation
por: Fu, Jinbo, et al.
Publicado: (2019)

The role of GLI1 for 5-Fu resistance in colorectal cancer
por: Zhang, Lining, et al.
Publicado: (2017)

Determination of Optimal Vitamin D Dosage in Children with Cholestasis
por: Chongthavornvasana, Sirada, et al.
Publicado: (2023)

XPF–ERCC1 Blocker Improves the Therapeutic Efficacy of 5-FU- and Oxaliplatin-Based Chemoradiotherapy in Colorectal Cancer
por: Huang, Ming-Yii, et al.
Publicado: (2023)

Managing 5FU Cardiotoxicity in Colorectal Cancer Treatment
por: Anaka, Matthew, et al.
Publicado: (2022)

Inhibition of CDK1 Reverses the Resistance of 5-Fu in Colorectal Cancer
por: Zhu, Yiping, et al.
Publicado: (2020)

Loss of ABCB4 attenuates the caspase-dependent apoptosis regulating resistance to 5-Fu in colorectal cancer
por: Hu, Hanqing, et al.
Publicado: (2018)

The fusion–fission optimization (FuFiO) algorithm
por: Nouhi, Behnaz, et al.
Publicado: (2022)

METTL3 antagonizes 5-FU chemotherapy and confers drug resistance in colorectal carcinoma
por: Li, Min, et al.
Publicado: (2022)

METTL3 antagonizes 5-FU chemotherapy and confers drug resistance in colorectal carcinoma
por: Li, Min, et al.
Publicado: (2023)

RETRACTED ARTICLE: Inhibition of EZH2 enhances the therapeutic effect of 5-FU via PUMA upregulation in colorectal cancer
por: Tan, Xiao, et al.
Publicado: (2020)

Retraction Note: Inhibition of EZH2 enhances the therapeutic effect of 5-FU via PUMA upregulation in colorectal cancer
por: Tan, Xiao, et al.
Publicado: (2023)

Personalized Medicine in Ophthalmology: From Pharmacogenetic Biomarkers to Therapeutic and Dosage Optimization
por: Ong, Frank S., et al.
Publicado: (2013)

Optimization and validation of spectrophotometric methods for determination of finasteride in dosage and biological forms
por: Amin, Alaa S., et al.
Publicado: (2012)

Association of 5-FU Therapeutic Drug Monitoring to DPD Phenotype Assessment May Reduce 5-FU Under-Exposure
por: Dolat, Marine, et al.
Publicado: (2020)

Knockout of SIRT4 decreases chemosensitivity to 5-FU in colorectal cancer cells
por: Zhu, Yuanyuan, et al.
Publicado: (2018)

Influence of Fiber Type and Dosage on Tensile Property of Asphalt Mixture Using Direct Tensile Test
por: Yang, Shuyao, et al.
Publicado: (2023)

Combinational inhibition of EGFR and YAP reverses 5-Fu resistance in colorectal cancer
por: Huang, Changhao, et al.
Publicado: (2020)

Evaluation of genetic diversity and population structure in Leptobotiamicrophthalma Fu & Ye, 1983 (Cypriniformes, Cobitidae)
por: Liu, Dongqi, et al.
Publicado: (2022)

Wnt pathway is involved in 5-FU drug resistance of colorectal cancer cells
por: He, Lingfeng, et al.
Publicado: (2018)

Optimized and Validated Spectrophotometric Methods for the Determination of Enalapril Maleate in Commercial Dosage Forms
por: Rahman, Nafisur, et al.
Publicado: (2008)

The Effect of Optimized Ultrafiltration on Perioperative Pulmonary Function During Cardiopulmonary Bypass in Infants Under 10 kg
por: Niu, Jianhong, et al.
Publicado: (2021)

Optimal dosage of cefmetazole for intraoperative antimicrobial prophylaxis in patients undergoing surgery for colorectal cancer
por: Tomizawa, Atsushi, et al.
Publicado: (2017)

Optimal ICG dosage of preoperative colonoscopic tattooing for fluorescence-guided laparoscopic colorectal surgery
por: Ahn, Hong-min, et al.
Publicado: (2021)

LINC02418 upregulates EPHA2 by competitively sponging miR-372-3p to promote 5-Fu/DDP chemoresistance in colorectal cancer
por: Yao, Fei, et al.
Publicado: (2022)

Up-regulation of FAT4 enhances the chemosensitivity of colorectal cancer cells treated by 5-FU
por: Li, Qianyuan, et al.
Publicado: (2020)

Halofuginone inhibits tumorigenic progression of 5-FU-resistant human colorectal cancer HCT-15/FU cells by targeting miR-132-3p in vitro
por: Wang, Chen, et al.
Publicado: (2020)

5-FU Metabolism in Cancer and Orally-Administrable 5-FU Drugs
por: Miura, Koh, et al.
Publicado: (2010)

Author Correction: The fusion–fission optimization (FuFiO) algorithm
por: Nouhi, Behnaz, et al.
Publicado: (2022)

PP2AC Level Determines Differential Programming of p38-TSC-mTOR Signaling and Therapeutic Response to p38-Targeted Therapy in Colorectal Cancer
por: Zhang, Yanjie, et al.
Publicado: (2015)

Uncovering the potential mechanism of Xue Fu Zhu Yu Decoction in the treatment of intracerebral hemorrhage
por: Xue, Dao-jin, et al.
Publicado: (2022)

NDRG4 sensitizes CRC cells to 5-FU by upregulating DDIT3 expression
por: Li, Ruikai, et al.
Publicado: (2021)

NDRG4 sensitizes CRC cells to 5-FU by upregulating DDIT3 expression
por: Li, Ruikai, et al.
Publicado: (2022)

Optimal control for colistin dosage selection
por: Gontijo, Aline Vidal Lacerda, et al.
Publicado: (2021)

5-FU-hydrogel inhibits colorectal peritoneal carcinomatosis and tumor growth in mice
por: Wang, Yongsheng, et al.
Publicado: (2010)

Overexpression of sortilin is associated with 5‐FU resistance and poor prognosis in colorectal cancer
por: Blondy, Sabrina, et al.
Publicado: (2020)

Synthesis and Chemopreventive Potential of 5-FU/Genistein Hybrids on Colorectal Cancer Cells
por: Moreno-Quintero, Gustavo, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qogn2acplnjjtirqk4mvlso7q4