A Novel Pan-Genome Reverse Vaccinology Approach Employing a Negative-Selection Strategy for Screening Surface-Exposed Antigens against leptospirosis

Reverse vaccinology (RV) has been widely used for screening of surface-exposed proteins (PSEs) of important pathogens, including outer membrane proteins (OMPs), and extracellular proteins (ECPs) as potential vaccine candidates. In this study, we applied a novel RV negative strategy and a pan-genome...

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Detalles Bibliográficos
Autores principales: Zeng, LingBing, Wang, Dongliang, Hu, NiYa, Zhu, Qing, Chen, Kaishen, Dong, Ke, Zhang, Yan, Yao, YuFeng, Guo, XiaoKui, Chang, Yung-Fu, Zhu, YongZhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348505/
https://www.ncbi.nlm.nih.gov/pubmed/28352257
http://dx.doi.org/10.3389/fmicb.2017.00396

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