A recurrent endometrial stromal sarcoma harbors the novel fusion JAZF1-BCORL1

• Genomic alterations may improve diagnostic certainty and subsequent treatment of endometrial stromal sarcoma. • Novel JAZF1-BCORL1 mutation was identified. • Targeted therapeutics to down-stream targets may improve survival benefit in these patients.

Detalles Bibliográficos
Autores principales: Allen, Allison J, Ali, Siraj M., Gowen, Kyle, Elvin, Julia A., Pejovic, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348601/
https://www.ncbi.nlm.nih.gov/pubmed/28331900
http://dx.doi.org/10.1016/j.gore.2017.03.002
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author Allen, Allison J
Ali, Siraj M.
Gowen, Kyle
Elvin, Julia A.
Pejovic, Tanja
author_facet Allen, Allison J
Ali, Siraj M.
Gowen, Kyle
Elvin, Julia A.
Pejovic, Tanja
author_sort Allen, Allison J
collection PubMed
description • Genomic alterations may improve diagnostic certainty and subsequent treatment of endometrial stromal sarcoma. • Novel JAZF1-BCORL1 mutation was identified. • Targeted therapeutics to down-stream targets may improve survival benefit in these patients.
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spelling pubmed-53486012017-03-22 A recurrent endometrial stromal sarcoma harbors the novel fusion JAZF1-BCORL1 Allen, Allison J Ali, Siraj M. Gowen, Kyle Elvin, Julia A. Pejovic, Tanja Gynecol Oncol Rep Case Report • Genomic alterations may improve diagnostic certainty and subsequent treatment of endometrial stromal sarcoma. • Novel JAZF1-BCORL1 mutation was identified. • Targeted therapeutics to down-stream targets may improve survival benefit in these patients. Elsevier 2017-03-08 /pmc/articles/PMC5348601/ /pubmed/28331900 http://dx.doi.org/10.1016/j.gore.2017.03.002 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Allen, Allison J
Ali, Siraj M.
Gowen, Kyle
Elvin, Julia A.
Pejovic, Tanja
A recurrent endometrial stromal sarcoma harbors the novel fusion JAZF1-BCORL1
title A recurrent endometrial stromal sarcoma harbors the novel fusion JAZF1-BCORL1
title_full A recurrent endometrial stromal sarcoma harbors the novel fusion JAZF1-BCORL1
title_fullStr A recurrent endometrial stromal sarcoma harbors the novel fusion JAZF1-BCORL1
title_full_unstemmed A recurrent endometrial stromal sarcoma harbors the novel fusion JAZF1-BCORL1
title_short A recurrent endometrial stromal sarcoma harbors the novel fusion JAZF1-BCORL1
title_sort recurrent endometrial stromal sarcoma harbors the novel fusion jazf1-bcorl1
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348601/
https://www.ncbi.nlm.nih.gov/pubmed/28331900
http://dx.doi.org/10.1016/j.gore.2017.03.002
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