A mutant Tat protein inhibits infection of human cells by strains from diverse HIV-1 subtypes

BACKGROUND: Nullbasic is a mutant HIV-1 Tat protein that inhibits HIV-1 replication via three independent mechanisms that disrupts 1) reverse transcription of the viral RNA genome into a DNA copy, 2) HIV-1 Rev protein function required for viral mRNA transport from the nucleus to the cytoplasm and 3...

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Detalles Bibliográficos
Autores principales: Rustanti, Lina, Jin, Hongping, Lor, Mary, Lin, Min Hsuan, Rawle, Daniel J., Harrich, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348743/
https://www.ncbi.nlm.nih.gov/pubmed/28288662
http://dx.doi.org/10.1186/s12985-017-0705-9

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