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Mesothelin promotes epithelial-to-mesenchymal transition and tumorigenicity of human lung cancer and mesothelioma cells

BACKGROUND: Lung cancer and pleural mesothelioma are two of the most deadly forms of cancer. The prognosis of lung cancer and mesothelioma is extremely poor due to limited treatment modalities and lack of understanding of the disease mechanisms. We have identified mesothelin as a potentially unique...

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Detalles Bibliográficos
Autores principales: He, Xiaoqing, Wang, Liying, Riedel, Heimo, Wang, Kai, Yang, Yong, Dinu, Cerasela Zoica, Rojanasakul, Yon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348784/
https://www.ncbi.nlm.nih.gov/pubmed/28288645
http://dx.doi.org/10.1186/s12943-017-0633-8