Cargando…

Overexpression of G protein-coupled receptor GPR87 promotes pancreatic cancer aggressiveness and activates NF-κB signaling pathway

BACKGROUND: Pancreatic cancer is a highly lethal disease and has the worst prognosis of any major malignancy. G protein-coupled receptor GPR87 is reported to be overexpressed in multiple cancers. The clinical significance and biological role of GPR87 in pancreatic cancer, however, remain to be estab...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Li, Zhou, Wei, Zhong, Yunfeng, Huo, Yongbao, Fan, Ping, Zhan, Sudong, Xiao, Jun, Jin, Xin, Gou, Shanmiao, Yin, Tao, Wu, Heshui, Liu, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348802/ https://www.ncbi.nlm.nih.gov/pubmed/28288630 http://dx.doi.org/10.1186/s12943-017-0627-6

Ejemplares similares

GPR87 Is an Overexpressed G-Protein Coupled Receptor in Squamous Cell Carcinoma of the Lung
por: Gugger, Mathias, et al.
Publicado: (2008)

Use of probiotics in the treatment of severe acute pancreatitis: a systematic review and meta-analysis of randomized controlled trials
por: Gou, Shanmiao, et al.
Publicado: (2014)

Overexpression of YBX1 Promotes Pancreatic Ductal Adenocarcinoma Growth via the GSK3B/Cyclin D1/Cyclin E1 Pathway
por: Liu, Zhiqiang, et al.
Publicado: (2020)

G Protein-Coupled Receptor 87 (GPR87) Promotes Cell Proliferation in Human Bladder Cancer Cells
por: Zhang, Xia, et al.
Publicado: (2015)

MiR-744 increases tumorigenicity of pancreatic cancer by activating Wnt/β-catenin pathway
por: Zhou, Wei, et al.
Publicado: (2015)

The Reduction of Peripheral Blood CD4(+) T Cell Indicates Persistent Organ Failure in Acute Pancreatitis
por: Yang, Zhiyong, et al.
Publicado: (2015)

G Protein-Coupled Receptor 87 (GPR87) Promotes the Growth and Metastasis of CD133(+) Cancer Stem-Like Cells in Hepatocellular Carcinoma
por: Yan, Mingxia, et al.
Publicado: (2013)

Expression and Role of GPR87 in Urothelial Carcinoma of the Bladder
por: Okazoe, Homare, et al.
Publicado: (2013)

Prediction of Severe Acute Pancreatitis Using a Decision Tree Model Based on the Revised Atlanta Classification of Acute Pancreatitis
por: Yang, Zhiyong, et al.
Publicado: (2015)

High Mobility Group Box Protein 1 Boosts Endothelial Albumin Transcytosis through the RAGE/Src/Caveolin-1 Pathway
por: Shang, Dan, et al.
Publicado: (2016)

Centrosomal protein 55 activates NF-κB signalling and promotes pancreatic cancer cells aggressiveness
por: Peng, Tao, et al.
Publicado: (2017)

MicroRNA-323-3p inhibits cell invasion and metastasis in pancreatic ductal adenocarcinoma via direct suppression of SMAD2 and SMAD3
por: Wang, Chunyou, et al.
Publicado: (2016)

Near-infrared photoimmunotherapy targeting GPR87: Development of a humanised anti-GPR87 mAb and therapeutic efficacy on a lung cancer mouse model
por: Yasui, Hirotoshi, et al.
Publicado: (2021)

Dendritic Cells Loaded with Pancreatic Cancer Stem Cells (CSCs) Lysates Induce Antitumor Immune Killing Effect In Vitro
por: Yin, Tao, et al.
Publicado: (2014)

Overexpression of PIMREG promotes breast cancer aggressiveness via constitutive activation of NF-κB signaling
por: Jiang, Lili, et al.
Publicado: (2019)

A Population-Based Study of the Incidence and Survival of Anorectal Gastrointestinal Stromal Tumor
por: Liu, Zhiqiang, et al.
Publicado: (2019)

Targeting GPR65 alleviates hepatic inflammation and fibrosis by suppressing the JNK and NF-κB pathways
por: Zhang, Kun, et al.
Publicado: (2023)

Low Concentrations of Metformin Selectively Inhibit CD133(+) Cell Proliferation in Pancreatic Cancer and Have Anticancer Action
por: Gou, Shanmiao, et al.
Publicado: (2013)

Critical role of NF-κB in pancreatic cancer
por: Prabhu, Lakshmi, et al.
Publicado: (2014)

G Protein-Coupled Receptor GPR87 Promotes the Expansion of PDA Stem Cells through Activating JAK2/STAT3
por: Jiang, Jianxin, et al.
Publicado: (2020)

Inverted U-Shaped Relationship between Central Venous Pressure and Intra-Abdominal Pressure in the Early Phase of Severe Acute Pancreatitis: A Retrospective Study
por: Yang, Chong, et al.
Publicado: (2015)

GPR87 Promotes Metastasis through the AKT-eNOS-NO Axis in Lung Adenocarcinoma
por: Ahn, Hye-Mi, et al.
Publicado: (2021)

GPR87 promotes tumor cell invasion and mediates the immunogenomic landscape of lung adenocarcinoma
por: Bai, Rui, et al.
Publicado: (2022)

Prognostic accuracy of the serum lactate level, the SOFA score and the qSOFA score for mortality among adults with Sepsis
por: Liu, Zhiqiang, et al.
Publicado: (2019)

Constitutive activation and overexpression of NF-κB/c-Rel in conjunction with p50 contribute to aggressive tongue tumorigenesis
por: Gupta, Shilpi, et al.
Publicado: (2018)

Overexpression of TRIM14 promotes tongue squamous cell carcinoma aggressiveness by activating the NF-κB signaling pathway
por: Su, Xuan, et al.
Publicado: (2016)

Valproic acid sensitizes pancreatic cancer cells to natural killer cell-mediated lysis by upregulating MICA and MICB via the PI3K/Akt signaling pathway
por: Shi, Pengfei, et al.
Publicado: (2014)

SPRR3 Contributes to Aggressiveness of Pancreatic Cancer Cells via NF-κB Signaling Pathway
por: Xie, Yuankang, et al.
Publicado: (2023)

The effect of metformin on survival of patients with pancreatic cancer: a meta-analysis
por: Li, Xiaogang, et al.
Publicado: (2017)

Soluble B7-H3 promotes the invasion and metastasis of pancreatic carcinoma cells through the TLR4/NF-κB pathway
por: Xie, Chao, et al.
Publicado: (2016)

Angiogenin Promotes U87MG Cell Proliferation by Activating NF-κB Signaling Pathway and Downregulating Its Binding Partner FHL3
por: Xia, Wenrong, et al.
Publicado: (2015)

Differential Gene Expression in GPR40-Overexpressing Pancreatic β-cells Treated with Linoleic Acid
por: Kim, In-Su, et al.
Publicado: (2015)

Tumor Cell Derived Exosomal GOT1 Suppresses Tumor Cell Ferroptosis to Accelerate Pancreatic Cancer Progression by Activating Nrf2/HO-1 Axis via Upregulating CCR2 Expression
por: Guo, Yao, et al.
Publicado: (2022)

Overexpression of GPR41 attenuated glucose production in propionate-induced bovine hepatocytes
por: Lin, Miao, et al.
Publicado: (2022)

Aberrant Activation of NF-κB Signalling in Aggressive Lymphoid Malignancies
por: Kennedy, Ruth, et al.
Publicado: (2018)

TRIM29 Overexpression Promotes Proliferation and Survival of Bladder Cancer Cells through NF-κB Signaling
por: Tan, Shu-Tao, et al.
Publicado: (2016)

Active drain system with reticulated open-pore foam-surface dressing for postoperative pancreatic fistula in a rat model
por: Li, Yang, et al.
Publicado: (2021)

GPR108, an NF-κB activator suppressed by TIRAP, negatively regulates TLR-triggered immune responses
por: Dong, Danfeng, et al.
Publicado: (2018)

GPR125 positively regulates osteoclastogenesis potentially through AKT-NF-κB and MAPK signaling pathways
por: Tang, Chen-Yi, et al.
Publicado: (2022)

MIB1 upregulates IQGAP1 and promotes pancreatic cancer progression by inducing ST7 degradation
por: Zhang, Bin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_c0hoq8n08oerlb5i91tk0pc95s