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Adipose tissue fibrosis in human cancer cachexia: the role of TGFβ pathway

BACKGROUND: Cancer cachexia is a multifactorial syndrome that dramatically decreases survival. Loss of white adipose tissue (WAT) is one of the key characteristics of cachexia. WAT wasting is paralleled by microarchitectural remodeling in cachectic cancer patients. Fibrosis results from uncontrolled...

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Detalles Bibliográficos
Autores principales:	Alves, Michele Joana, Figuerêdo, Raquel Galvão, Azevedo, Flavia Figueiredo, Cavallaro, Diego Alexandre, Neto, Nelson Inácio Pinto, Lima, Joanna Darck Carola, Matos-Neto, Emidio, Radloff, Katrin, Riccardi, Daniela Mendes, Camargo, Rodolfo Gonzalez, De Alcântara, Paulo Sérgio Martins, Otoch, José Pinhata, Junior, Miguel Luiz Batista, Seelaender, Marília
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348844/ https://www.ncbi.nlm.nih.gov/pubmed/28288584 http://dx.doi.org/10.1186/s12885-017-3178-8

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