Cargando…

Aggregatibacter actinomycetemcomitans osteomyelitis in a 12 year old boy: case report emphasizing the importance of tissue culture, and review of literature

BACKGROUND: Aggregatibacter actinomycetemcomitans most commonly causes periodontitis but has been reported to infect heart valves, soft tissue, brain and lungs, and distal bones. Osteomyelitis distal to the jaw is rarely described. CASE PRESENTATION: We report an unusual and rare case of chronic ost...

Descripción completa

Detalles Bibliográficos
Autores principales: Sharma, Ketaki, Mudgil, Poonam, Whitehall, John S., Gosbell, Iain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348864/
https://www.ncbi.nlm.nih.gov/pubmed/28288638
http://dx.doi.org/10.1186/s12941-017-0186-0
_version_ 1782514341359124480
author Sharma, Ketaki
Mudgil, Poonam
Whitehall, John S.
Gosbell, Iain
author_facet Sharma, Ketaki
Mudgil, Poonam
Whitehall, John S.
Gosbell, Iain
author_sort Sharma, Ketaki
collection PubMed
description BACKGROUND: Aggregatibacter actinomycetemcomitans most commonly causes periodontitis but has been reported to infect heart valves, soft tissue, brain and lungs, and distal bones. Osteomyelitis distal to the jaw is rarely described. CASE PRESENTATION: We report an unusual and rare case of chronic osteomyelitis caused by A. actinomycetemcomitans in the toe of a paediatric patient, and review the available literature. The infection was managed with intravenous antibiotics followed by oral antibiotics. CONCLUSION: This is an unusual presentation of A. actinomycetemcomitans causing chronic osteomyelitis presumed due to nidation in a minimally damaged bone, associated with bacteraemia of an oral commensal. It occurred in the toe, without obvious dental predisposition; associated with minimal clinical disturbance and with muted immune response.
format Online
Article
Text
id pubmed-5348864
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-53488642017-03-14 Aggregatibacter actinomycetemcomitans osteomyelitis in a 12 year old boy: case report emphasizing the importance of tissue culture, and review of literature Sharma, Ketaki Mudgil, Poonam Whitehall, John S. Gosbell, Iain Ann Clin Microbiol Antimicrob Case Report BACKGROUND: Aggregatibacter actinomycetemcomitans most commonly causes periodontitis but has been reported to infect heart valves, soft tissue, brain and lungs, and distal bones. Osteomyelitis distal to the jaw is rarely described. CASE PRESENTATION: We report an unusual and rare case of chronic osteomyelitis caused by A. actinomycetemcomitans in the toe of a paediatric patient, and review the available literature. The infection was managed with intravenous antibiotics followed by oral antibiotics. CONCLUSION: This is an unusual presentation of A. actinomycetemcomitans causing chronic osteomyelitis presumed due to nidation in a minimally damaged bone, associated with bacteraemia of an oral commensal. It occurred in the toe, without obvious dental predisposition; associated with minimal clinical disturbance and with muted immune response. BioMed Central 2017-03-14 /pmc/articles/PMC5348864/ /pubmed/28288638 http://dx.doi.org/10.1186/s12941-017-0186-0 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Sharma, Ketaki
Mudgil, Poonam
Whitehall, John S.
Gosbell, Iain
Aggregatibacter actinomycetemcomitans osteomyelitis in a 12 year old boy: case report emphasizing the importance of tissue culture, and review of literature
title Aggregatibacter actinomycetemcomitans osteomyelitis in a 12 year old boy: case report emphasizing the importance of tissue culture, and review of literature
title_full Aggregatibacter actinomycetemcomitans osteomyelitis in a 12 year old boy: case report emphasizing the importance of tissue culture, and review of literature
title_fullStr Aggregatibacter actinomycetemcomitans osteomyelitis in a 12 year old boy: case report emphasizing the importance of tissue culture, and review of literature
title_full_unstemmed Aggregatibacter actinomycetemcomitans osteomyelitis in a 12 year old boy: case report emphasizing the importance of tissue culture, and review of literature
title_short Aggregatibacter actinomycetemcomitans osteomyelitis in a 12 year old boy: case report emphasizing the importance of tissue culture, and review of literature
title_sort aggregatibacter actinomycetemcomitans osteomyelitis in a 12 year old boy: case report emphasizing the importance of tissue culture, and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348864/
https://www.ncbi.nlm.nih.gov/pubmed/28288638
http://dx.doi.org/10.1186/s12941-017-0186-0
work_keys_str_mv AT sharmaketaki aggregatibacteractinomycetemcomitansosteomyelitisina12yearoldboycasereportemphasizingtheimportanceoftissuecultureandreviewofliterature
AT mudgilpoonam aggregatibacteractinomycetemcomitansosteomyelitisina12yearoldboycasereportemphasizingtheimportanceoftissuecultureandreviewofliterature
AT whitehalljohns aggregatibacteractinomycetemcomitansosteomyelitisina12yearoldboycasereportemphasizingtheimportanceoftissuecultureandreviewofliterature
AT gosbelliain aggregatibacteractinomycetemcomitansosteomyelitisina12yearoldboycasereportemphasizingtheimportanceoftissuecultureandreviewofliterature