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Effect of Moringa oleifera Lam. leaf powder on the pharmacokinetics of nevirapine in HIV-infected adults: a one sequence cross-over study
BACKGROUND: Moringa oleifera Lam., an herb commonly consumed by HIV-infected people on antiretroviral therapy, inhibits cytochrome P450 3A4, 1A2 and 2D6 activity in vitro; and may alter the pharmacokinetics (PK) of antiretroviral drugs metabolized via the same pathways. However, in vitro drug intera...
Autores principales: | Monera-Penduka, Tsitsi G., Maponga, Charles C., Wolfe, Alan R., Wiesner, Lubbe, Morse, Gene D., Nhachi, Charles F. B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348890/ https://www.ncbi.nlm.nih.gov/pubmed/28293270 http://dx.doi.org/10.1186/s12981-017-0140-4 |
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