Autophagy: one more Nobel Prize for yeast

The recent announcement of the 2016 Nobel Prize in Physiology or Medicine, awarded to Yoshinori Ohsumi for the discoveries of mechanisms governing autophagy, underscores the importance of intracellular degradation and recycling. At the same time, it further cements yeast, in which this field decisiv...

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Detalles Bibliográficos
Autores principales: Zimmermann, Andreas, Kainz, Katharina, Andryushkova, Aleksandra, Hofer, Sebastian, Madeo, Frank, Carmona-Gutierrez, Didac
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2016
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348976/
https://www.ncbi.nlm.nih.gov/pubmed/28357329
http://dx.doi.org/10.15698/mic2016.12.544
Descripción
Sumario:The recent announcement of the 2016 Nobel Prize in Physiology or Medicine, awarded to Yoshinori Ohsumi for the discoveries of mechanisms governing autophagy, underscores the importance of intracellular degradation and recycling. At the same time, it further cements yeast, in which this field decisively developed, as a prolific model organism. Here we provide a quick historical overview that mirrors both the importance of autophagy as a conserved and essential process for cellular life and death as well as the crucial role of yeast in its mechanistic characterization.

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