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The transcriptional repressor Sum1p counteracts Sir2p in regulation of the actin cytoskeleton, mitochondrial quality control and replicative lifespan in Saccharomyces cerevisiae

Increasing the stability or dynamics of the actin cytoskeleton can extend lifespan in C. elegans and S. cerevisiae. Actin cables of budding yeast, bundles of actin filaments that mediate cargo transport, affect lifespan control through effects on mitochondrial quality control. Sir2p, the founding me...

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Detalles Bibliográficos
Autores principales:	Higuchi-Sanabria, Ryo, Vevea, Jason D., Charalel, Joseph K., Sapar, Maria L., Pon, Liza A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shared Science Publishers OG 2016
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349106/ https://www.ncbi.nlm.nih.gov/pubmed/28357337 http://dx.doi.org/10.15698/mic2016.02.478

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