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Angiotensin II type 1 receptor blockers increase tolerance of cells to copper and cisplatin
The human pathology Wilson disease (WD) is characterized by toxic copper (Cu) accumulation in brain and liver, resulting in, among other indications, mitochondrial dysfunction and apoptosis of hepatocytes. In an effort to identify novel compounds that can alleviate Cu-induced toxicity, we screened t...
Autores principales: | Spincemaille, Pieter, Chandhok, Gursimran, Zibert, Andree, Schmidt, Hartmut, Verbeek, Jef, Chaltin, Patrick, Cammue, Bruno P., Cassiman, David, Thevissen, Karin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shared Science Publishers OG
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349125/ https://www.ncbi.nlm.nih.gov/pubmed/28357214 http://dx.doi.org/10.15698/mic2014.11.175 |
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